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Smart Storage Without the Premium: HPE P40543-B21 1.92TB Read-Intensive SATA SSD for ProLiant Gen10+ Servers

Smart Storage Without the Premium: HPE P40543-B21 1.92TB Read-Intensive SATA SSD for ProLiant Gen10+ Servers

HPE P40543-B21 1.92TB SATA SSD for ProLiant Gen10 Plus Servers: Cost Efficient Read Intensive Storage Built for Enterprise Reliability

The HPE P40543-B21 1.92TB 2.5inch Small Form Factor SATA Solid State Drive is designed for organizations that need dependable, enterprise grade storage without unnecessary complexity. Optimized for HPE ProLiant Gen10 Plus servers, this read intensive SSD delivers consistent performance, strong data protection through digitally signed firmware, and seamless integration with HPE server platforms. With its Basic Carrier design and SATA 6Gbps interface, the HPE P40543-B21 is an ideal solution for data centers focused on efficiency, scalability, and predictable workloads.

Overview of the HPE P40543-B21 Solid State Drive

The HPE P40543-B21 is a 1.92TB SATA SSD built specifically for read heavy enterprise workloads. It combines proven NAND flash technology with HPE validated firmware to ensure stable operation in 24x7 server environments. This drive is tailored for ProLiant Gen10 Plus servers, offering full compatibility with HPE RAID controllers, firmware, and management tools.

Key Features at a Glance

This SSD offers high usable capacity, enterprise level firmware security, and a compact 2.5inch SFF form factor. The Basic Carrier design provides a cost effective alternative for organizations that do not require Smart Carrier LEDs while still maintaining HPE certification and reliability.

Technical Specifications and Performance Characteristics

The HPE P40543-B21 is engineered to provide balanced performance and endurance for modern server workloads that prioritize reads over writes.

Capacity and Form Factor

With a capacity of 1.92TB, the drive supports a wide range of applications including operating systems, virtual machine storage, application data, and frequently accessed content. The 2.5inch Small Form Factor enables high density server configurations and efficient airflow within rack systems.

SATA 6Gbps Interface

The SATA 6Gbps interface ensures broad compatibility and stable throughput across ProLiant Gen10 Plus platforms. While SATA focuses on reliability rather than peak speed, it delivers consistent latency and dependable performance for enterprise workloads.

Read Intensive Optimization

As a read intensive SSD, the HPE P40543-B21 is optimized for scenarios where data is accessed far more often than it is written. This makes it well suited for boot drives, read heavy databases, analytics reporting, and content delivery systems.

Digitally Signed Firmware for Enhanced Security

Firmware security is a critical requirement in enterprise IT environments, and HPE addresses this with digitally signed firmware.

Firmware Integrity and Protection

Digitally signed firmware ensures that only authenticated and HPE approved firmware can run on the SSD. This prevents unauthorized modifications and reduces the risk of firmware based attacks.

Enterprise Compliance and Trust

For organizations operating under strict compliance requirements, digitally signed firmware adds an important layer of assurance, helping maintain system integrity and audit readiness.

Basic Carrier Design and Practical Benefits

The HPE P40543-B21 uses a Basic Carrier rather than a Smart Carrier, making it a practical choice for cost conscious deployments.

Streamlined Carrier Functionality

The Basic Carrier provides secure physical installation and reliable connectivity without integrated LED indicators. This design is ideal for environments where centralized monitoring tools are used instead of visual status indicators.

Lower Cost Without Compromising Quality

By choosing a Basic Carrier, organizations can reduce hardware costs while still benefiting from HPE certified firmware, compatibility, and support.

Compatibility with ProLiant Gen10 Plus Servers

This SSD is purpose built for HPE ProLiant Gen10 Plus servers, ensuring smooth deployment and long term support.

Certified Integration with HPE Ecosystem

HPE certification guarantees compatibility with server BIOS, RAID controllers, and management software. This minimizes deployment risks and ensures predictable behavior throughout the server lifecycle.

Optimized for Gen10 Plus Architectures

ProLiant Gen10 Plus servers offer enhanced performance, security, and manageability. The HPE P40543-B21 complements these capabilities by providing stable, enterprise ready storage optimized for modern workloads.

Reliability and Endurance for Continuous Operation

Enterprise servers require storage that can operate continuously under load.

Consistent Performance Under Read Heavy Loads

The drive is designed to maintain steady performance even during sustained read operations, making it suitable for production environments with predictable access patterns.

Built for 24x7 Data Center Use

The HPE P40543-B21 is engineered for nonstop operation, supporting business critical applications where uptime and data availability are essential.

Ideal Use Cases for HPE P40543-B21 SSD

This SSD is versatile and well suited for a variety of enterprise scenarios.

Boot and Operating System Drives

Its reliability and read optimized design make it an excellent choice for server boot volumes and operating system storage.

Virtualization and Application Hosting

The drive supports virtual machines, containers, and enterprise applications that require fast and consistent read access.

Web Services and Content Platforms

Web hosting environments and content delivery systems benefit from the SSD’s stable read performance and low latency.

Cost Efficiency and Total Cost of Ownership

The HPE P40543-B21 is designed to deliver long term value.

Affordable Enterprise Storage Solution

By combining SATA technology with read intensive optimization, this SSD offers enterprise reliability at a lower cost compared to write intensive or NVMe alternatives.

Reduced Maintenance and Downtime

HPE validated firmware and predictable endurance help reduce unexpected failures, lowering operational costs and improving overall system reliability.

Why Choose HPE P40543-B21 for ProLiant Gen10 Plus Servers

The HPE P40543-B21 1.92TB SATA SSD is a smart choice for organizations seeking secure, reliable, and cost effective enterprise storage. With digitally signed firmware, a practical Basic Carrier design, and full compatibility with ProLiant Gen10 Plus servers, it delivers dependable performance for read intensive workloads. For data centers focused on efficiency, stability, and long term value, this SSD provides a balanced and trusted storage solution.

Feb 12th 2026 Mike Anderson

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